Rare Esotropia Side Effect from 0.01% Atropine for Myopia Control in Kids

Imagine a world where a simple eye drop treatment, designed to help children with myopia, could unexpectedly lead to a rare eye condition. This is the story of a young boy and his journey with esotropia, a condition that turned his vision upside down.

Myopia, or nearsightedness, is a common visual impairment, especially among children, and it’s on the rise. Fortunately, a low-dose atropine treatment has emerged as a promising solution, offering effective control with minimal side effects. However, as with any medical intervention, rare complications can occur, and this is where our story begins.

An 8-year-old boy, with a family history of high myopia, presented with gradually worsening vision. Despite his previous glasses, his vision continued to blur. After a thorough examination, it was discovered that his axial length, a key indicator of myopia, had significantly increased. The treatment plan included a short course of 0.01% atropine eye drops to slow this progression.

But here’s where it gets controversial: after just three months of treatment, the boy started experiencing double vision. Further tests revealed a rare case of acquired esotropia, a type of eye misalignment. The atropine, a drug known to affect accommodation, seemed to have triggered this unexpected side effect.

And this is the part most people miss: the impact of atropine on binocular vision. In this case, the drug’s interference with accommodation may have led to excessive convergence, causing the esotropia. This highlights the delicate balance between effective myopia control and preserving normal binocular function.

The solution? Discontinuing atropine and introducing an alternative: multifocal soft contact lenses. These lenses, by creating a myopic defocus, not only slowed axial elongation but also restored the boy’s binocular vision.

The anticholinergic effect of atropine, which partially inhibits peripheral accommodation, could also have played a role in the development of esotropia. This effect has been documented with other anticholinergic medications, further emphasizing the need for caution and close monitoring when using atropine.

In conclusion, while low-dose atropine is generally considered safe and effective for myopia control, it’s crucial to recognize and address rare complications like esotropia. The case highlights the importance of individualized treatment plans and the need for further research to understand the full impact of atropine on binocular vision.

So, what do you think? Should we be more cautious with atropine treatment, especially in cases of high myopia? Or do the benefits still outweigh the risks? We’d love to hear your thoughts in the comments!

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